pentobarbital will reduce the extent or impact of nilotinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will lower the level or effect of acalabrutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Contraindicated (1)pentobarbital decreases amounts of vandetanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay clear of coadministration with powerful CYP3A4 inducers; these medications lessen publicity to vandetanib by nearly forty%.

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pentobarbital will lower the level or impact of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

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pentobarbital will lessen the level or outcome of dutasteride by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.

pentobarbital boosts toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 check here metabolism. Use Warning/Check. CYP3A4 inducers may improve the metabolism of ifosfamide to its active alkylating metabolites.

pentobarbital will lower the extent or effect of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will reduce the level or result of larotrectinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

Reserve concomitant prescribing of these prescription drugs in clients for whom other cure possibilities are inadequate. Limit dosages and durations to the minimal demanded. Monitor closely for indications of respiratory despair and sedation.

pentobarbital will minimize the extent or impact of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers can lead to decreased serum concentrations and lack of antimalarial efficacy

pentobarbital boosts toxicity of methoxyflurane by raising metabolism. Contraindicated. Enhanced metabolism of methoxyflurane to nephrotoxic compounds.

pentobarbital will minimize the level or outcome of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.